Salsprin Injection

Sodium salicylate 250 mg/mL

Sodium salicylate produces irreversible inhibition of the cyclo-oxygenase step of arachidonic acid metabolism, leading to a suppression of prostaglandin production in all metabolic systems. The duration of action allows a twelve-hour dosage regime for inflammatory conditions. Thrombosis inhibition requires administration every 2 – 7 days, depending on the dose.

SALSPRIN is indicated for the control of fever and/or pain, as well as for control of inappropriate thrombosis in the horse and camel.

Salicylate has a half-life of 1 hour in the horse, and is rapidly cleared from the body. Onset of action is approximately 10 – 15 minutes. The pharmacological effects of the salicylate are, however, considerably more prolonged than this, due to the irreversible nature of the action. 

SALSPRIN will not control severe visceral pain, or sharp or excruciating pain due to severe wounds or fractures.

Musculo-skeletal: Short term treatment of mild joint and connective tissue disease, osteoarthritis, tendon and ligament sprains and exertional myopathy.

Pyrexia: Symptomatic suppression of fever in situations where the pyrexia is inappropriate or excessive.

Thrombosis: Prevention or reduction of thrombosis when it plays a part in disease aetiology (such as pedal thrombotic conditions).

Horses:

Anti-inflammatory Effect: 

• 35 – 45 mg/kg every 8 – 12 hours 
• Administer by slow intravenous (IV) injection 

Anti-thrombotic Effect:

• 5 mg/kg every second day
• Or 20 mg/kg every 5th day by slow intravenous (IV) injection

Camels:

• 25 mg/kg (10 mL per 100kg) every 24 hours

• Administer by slow intravenous (IV) injection

Users must adhere to local and racing regulations.

WARNINGS: Always consult label and leaflet for restraints, contraindications, precautions and side effects.