Thiazine 100 Injection

Xylazine (as hydrochloride) 100 mg/mL

Xylazine is a non-narcotic sedative, analgesic and muscle relaxant with a rapid therapeutic response expected within 1 – 5 minutes of intravenous injection. Sedation is maintained for 1 – 2 hours, while significant levels of analgesia last 15 – 30 minutes. The duration and depth of analgesia and sedation achieved are dependent on dose and the temperament of the animal.

THIAZINE 100 has many clinical applications, including:

Radiography: To calm animals and reduce movement during radiography.

Diagnostic Procedures: To keep animal calm and quiet during more painful &/or intricate procedures, such as endoscopy, catheterisation, peritoneal tap or ophthalmic, rectal or vaginal examinations.

Minor Surgical Procedures: To assist with procedures such as bandage changes, cast application and removal, and minor suturing and surgical procedures under local anaesthesia.

Anaesthesia: In combination with Ketamine to induce full surgical anaesthesia. Post-anaesthesia to smooth difficult recoveries.

Spasmodic Colic: THIAZINE 100 may be used as an analgesic/sedative in spasmodic (hypermotility) colic, however it is contraindicated in cases of obstructive colic or ileus as xylazine will further reduce gut motility.

This guide should be considered as a base from which dosage can be modified to effect, according to the depth and duration of analgesia or sedation required.

Horses:

For Mild Sedation: Give 0.25 – 0.5 mg/kg by slow intravenous (IV) injection 

(i.e. 0.25 – 0.5 mL per 100 kg bodyweight)

For Heavy Sedation: Give 1.1 mg/kg by slow intravenous (IV) injection 

(i.e. 1.1 mL per 100 kg bodyweight)

For Heavy Sedation: Give 2.2 mg/kg by intravenous (IV) injection 

(i.e. 2.2 mL per 100 kg bodyweight)

For treating Spasmodic Colic:  Give 0.5 mg/kg by slow intravenous (IV) injection

(i.e. 0.5 mL per kg bodyweight)

Intravenous administration induces a more rapid response, of shorter duration, than with intramuscular administration. Any unused portion of product should be discarded 3 months after first broaching the vial.

Camels:

• For sedation, use 50-80 mg (0.5 – 0.8 mL) by slow intravenous (IV) injection, depending on camel size
• For light anaesthesia, use 120 – 150 mg (1.2 – 1.5 mL) by slow intravenous (IV) injection, depending on camel size

It is common to follow with an atipamazole hydrochloride product such as Reversamed

Users must adhere to local and racing regulations.

WARNINGS: Always consult label and leaflet for restraints, contraindications, precautions and side effects.